| 摘要: | 過敏性鼻炎是常見之慢性病，是一種人體接觸或吸入致敏原後，體内的免疫球蛋白E (IgE)導致肥大細胞釋放組織胺，所產生的造成過敏反應，常造成眼睛瘙癢、鼻部癢、鼻塞、流鼻涕、打噴嚏、鼻竇炎、哮喘甚至蓴麻疹，嚴重影響生活品質，2013年健保資料顯示花粉熱及過敏性鼻炎門診 就診人次合計4181974人次，約佔總人口數的17.8%。目前，過敏性鼻炎的治療是以避免過敏原，藥物治療，以及手術治療為主，但是，這些治療仍存在治療效果不佳，並可能有副作用。因此，尋找其他有效的輔助方法，將有助於過敏性鼻炎的治療。本研究計晝擬進行兩年之研究於大林慈濟醫院耳鼻喉科門診收案，採立意隨機分配方式取樣，實驗組及對照組各51名，以遠紅外線熱敷眼鼻部、頭肩頸背部及腰背部，涵蓋大椎、定喘、風門、 肺俞、脾俞、腎俞等穴位，每天1次，每次40分鐘，為時三個月，並抽血檢驗總IgE及嗜酸性細胞陽離子蛋白（eosinophil cationic protein)數值之變化，並以台灣版SNOT-20鼻及鼻竇炎評估量表 及WHOQOL-BREF以台灣簡明版世界衛生組織生活品質問卷，以了解透過遠紅外線熱敷是否可有效改善打噴嚏、流鼻涕、鼻塞及鼻、眼結膜癢過敏等症狀，以及對生活品質促進之效益。結合中醫穴位照射及西醫抗組織胺及類固醇鼻劑治療過敏性鼻炎原則，近期透過人體試驗 pre-test結果發現，遠紅外線可以改善自律神經系統趨向正常運作，對於血管性、特異或非特異性過敏性鼻炎改善血液循環及緩解過敏不適等症狀及免疫功能提升。因此，遠紅外線理論上對於過敏性鼻炎有一定療效合併藥物治療可以短期更有效改善症狀及長期達到治癒預期結果。本研究成果可促進遠紅外線在過敏性鼻炎輔助治療上的推廣，並可提供醫師及過敏性鼻炎病患一種非侵入性的預防或輔助療法選擇，降低患者個人不適和公共健康保險支出。
Allergic rhinitis (AR) is one of the common chronic diseases, which can seriously decrease patient’s life quality due to sneezing, itchy and watery eyes, swelling and inflammation of the nasal passages, and an increase in mucus production. The outpatient services for AR in 2013 were 4181974 according to the statistical data from the National Health Insurance Administration of Taiwan. Presently, AR is mainly treated by allergen prevention, medicine and operation; however, the efficacy is generally unsatisfied and side effects are usually accompanied. Accordingly, to develop other effective complementary treatments will be beneficial to AR patients. This project is planned to be carried out in the Otolaryngological Department of Dalin Buddhist Tzu Chi Hospital for two years. The recruited subjects will be randomly allocated into the experimental or control group (51 subjects each) and treated by far-infrared hot compress (FIRHC) in regions covering eyes, nose, head, neck, shoulders, back and waist (including acupoints of DU14, EX-B1, BL12, BL13, BL20 and BL23) for 40 min per day for 3 months. Total IgE and eosinophil cationic protein in blood as well as a questionnaire survey by SNOT-20 and WHOQOL-BREF tests will be examined before and after the trial to investigate the effect of FIRHC on the symptoms of AR and the promotion of life quality. Recently, we have complementarily applied FIRHC to AR patients with traditional medical care in the pre-test, which explored that FIRHC is able to balance the activity of sympathetic and parasympathetic nervous systems, improve the symptoms of AR and increase immunity. Accordingly, we predict FIRHC to be a promising complementary treatment of pharmaceuticals for AR, which provides AR patients a non-intrusive medical care or prevention alternative to traditional medicine, and so that to decrease personal uncomfortableness and expenditure of public health insu「3nc㊀. |
