本研究分析養殖九孔之鋅生物累積動力行為及急性毒以評估鋅之生物濃縮及毒性特性。以14天實驗室暴露試驗推估九孔在餵食與非餵食狀況下對鋅之吸收及排除速率常數(即，k₁及k₂)，其中亦決定生物濃縮因子(BCF)。一階單區塊模式可成功地推求出毒物動力常數k₁及k₂。結果九孔在非餵食藻類狀況下暴露在1 mg L¯¹鋅濃度之k₁及k₂值分別為102.04 ± 23.2 ml g¯¹d¯¹及0.611 ± 0.43 d¯¹。當九孔在餵食狀況下，k₁及k₂值則分別為113.84 ± 24.4 g g¯¹d¯¹及0.636 ± 0.21 d¯¹。在餵食狀況下，九孔之軟體組織及殼之BCF值分別為179 ± 15及19 ± 4。由急性毒實驗結果得知九孔之96-h LC₅₀值為1.2 ± 0.4 mg L¯¹。LC₅₀值可由已知之暴露時間，k₂及BCF值，藉由一階單區塊模式預測得知。當暴露時間達無限時，推估九孔之起始LC₅₀值為0.987 mg L¯¹。
This work analyzed the Zn bioaccumulation kinetics and acute toxicity in the abalone Haliotis diversicolor supertexta for assessing bioconcentration and toxicity in an aquacultural system. A 14-d laboratory exposure experiment estimated uptake and depuration rate constants (k₁ and k₂, respectively) of H. diversicolor supertexta via nondietary and dietary processes. Bioconcentration factor (BCF) were determined. A simple first-order one-compartment model was successfully fitted the toxicokinetic parameters k₁ and k₂. The resulting values of k₁ and k₂ of H. diversicolor supertexta were 102.04±23.2 ml g¯¹ d¯¹ and 0.611±0.43 d¯¹, respectively, when the abalone were exposed to 1 mg L¯¹ Zn seawater without the presence of algae. When the abalone were fed with the algae, k₁ and k₂ values were estimated to be 113.84±24.4 g g¯¹ d¯¹ and 0.636±0.21 d¯¹, respectively. BCFs for the soft tissue and shell are 179±15 and 19±4, respectively in the food-exposed condition. The 96-h LC₅₀ for abalone was 1.2±0.4 mg L¯¹. LC₅₀ value could be predicted from the acknowledge of the exposure time, k₂, and BCF followed by the one-compartment model. When the exposure time approaches infinity, the incipient LC₅₀ value could be estimated. The incipient LC₅₀ value for the abalone was estimated to be 0.987 mg L¯¹.
